Johnny Galecki(The Big Ba..)
Galecki plays Dr. Leonard Hofstadter, an experimental physicist who is romantically challenged and lives with his friend in an apartment. He has one previous Emmy nomination for this role.
Jon Cryer(Two and a ..)
Cryer plays Alan Harper, a chiropractor and free-loader in Malibu. With new billing on the show, it is expected that he will move to the lead category from supporting, where he has one Emmy win in six nominations for this role.
Josh Radnor(How I Met ..)
Radnor plays Ted Mosby, a New York architect who enjoys hanging out with his four friends. He has no previous Emmy nominations for this role.
Kevin Connolly(Entourage)
Connolly plays Eric Murphy, best friend and manager of a young Hollywood superstar. He has no previous Emmy nominations for this role.
Larry David(Curb Your ..)
David plays a fictional version of himself, the wealthy creator of "Seinfeld" who struggles to conform to society's rules. He has four Emmy nominations for this role. He also has two previous wins in 18 other nominations.
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