Even though she has had no success at the Emmy Awards for her role on "Hot in Cleveland," Betty White is the reigning two-time champ as Best TV Comedy Actress at the Screen Actors Guild Awards. Recent Emmy winner and five-time SAG queen Julia Louis-Dreyfus ("Veep") is eligible for the first time and will be stiff competition.
All of last year's other nominees - Julie Bowen and Sofia Vergara ("Modern Family"), Edie Falco ("Nurse Jackie"), and Tina Fey ("30 Rock") - are also still eligible. Rookie contenders Zooey Deschanel ("New Girl"), Lena Dunham ("Girls"), and Mindy Kaling ("The Mindy Project") could also be threats, as would be the never-nominated Amy Poehler ("Parks and Recreation").
A few other possibilities include Christina Applegate and Maya Rudolph ("Up All Night"), Ellen Barkin ("The New Normal"), Kristen Bell ("House of Lies"), Mayim Bialik ("The Big Bang Theory"), Kat Dennings ("2 Broke Girls"), Patricia Heaton ("The Middle"), Cloris Leachman and Martha Plimpton ("Raising Hope"), Laura Linney ("The Big C"), Jane Lynch ("Glee"), Melissa McCarthy ("Mike and Molly"), and Mary-Louise Parker ("Weeds").