Wesley plays Tara Thornton, best friend to Sookie Stackhouse (Anna Paquin).
Devine plays Georgia. She has one previous Emmy win for her only career nomination.
Parrilla plays Evil Queen/Regina Mills. She has no previous Emmy nominations in her career.
Froggatt plays Anna. She has no previous Emmy nominations in her career.
Siff plays Tara Knowles. She has no previous Emmy nominations in her career.
Graham plays Sarah Braverman, a single mother who has moved into her parents' house. She has no previous Emmy nominations for this role.
McPhee plays Karen Cartwright, a small town woman auditioning to play Marilyn Monroe on Broadway. This is her first time eligible at the Emmys for this role.
Headey plays Queen Cersei Lannister, the villainous and murderous wife of King Robert Baratheon. She has no previous Emmy nominations for this role.
Gunn plays Skyler White, the smart and driven wife of a terminally ill teacher who becomes a drug dealer. She has no previous Emmy nominations for this role.
Jones plays Betty Draper Francis, a recently remarried woman and mother of three in the 1960s. She has one Emmy nomination for this role.
McDonnell plays Sharon Raydor, a Los Angeles police department captain. She has one previous Emmy nomination for this role and one other previous nomination.
Smith plays Violet Crawley, the sharp-tongued Dowager Countess of Grantham. She has two previous Emmy Award wins in five career nominations.
Gless plays Madeline Westen, a retired mother of a burned CIA agent in Miami. She has one Emmy nomination for this role. She has two previous wins in 10 overall nominations.
Oh plays Dr. Cristina Yang, an incredibly focused and driven doctor in Seattle. She has five Emmy nominations for this role.
Byrne plays Ellen Parsons, the conflicted protege of a hard-nosed litigator in New York. She has two Emmy nominations for this role.
King plays Lydia Adams, a Los Angeles police detective. She has no previous Emmy nominations for this role.
Baccarin plays Jessica Brody, the wife of a U.S. Marine who has just returned home after many years as a prisoner. This is her first time eligible at the Emmys for this role.
Potter plays Kristina Braverman, the mother of three children and a political campaign manager. She has no previous Emmy nominations for this role.
Forbes plays Rosie Larsen, a mother grieving for her murdered teenage daughter. She has one Emmy nomination for this role.
Hilty plays Ivy Lynn, a veteran actress auditioning to play Marilyn Monroe in a Broadway musical. This is her first time eligible at the Emmys for this role.
Shipka plays Sally Draper, the troubled oldest child of an advertising executive in the 1960s. She has no previous Emmy nominations for this role.
Macdonald plays Margaret Schroeder, a young Irish widow and mother who becomes the mistress of a political gangster. She has one Emmy nomination for this role. She has one previous win in her only other nomination.
Hennessy plays Dr. Jo Carter, the no-nonsense veterinarian at a horse track. This is her first time eligible at the Emmys for this role.
Carpenter plays Debra Morgan, a Miami police detective and adopted sister of a serial killer. She has no previous Emmy nominations for this role.
Mol plays Gillian Darmody, the mother of a gangster in Prohibition Era Atlantic City. She has no previous Emmy nominations for this role.
Clarke plays Dany Targaryen, the exiled daughter of the previous king and now part of the Dothraki army. She has no previous Emmy nominations for this role.
Nielsen plays Meredith Kane, the wife of a hard-nosed Chicago mayor. This is her first time eligible at the Emmys for this role.
Baranski plays Diane Lockhart, a very vocal senior partner at a law firm. She has two Emmy nominations for this role. She has one previous win in nine overall nominations.
Hendricks plays Joan Holloway Harris, the office manager for an advertising agency in the 1960s. She has two Emmy nominations for this role.
Wilson plays Dr. Miranda Bailey, an attending general surgeon at a Seattle hospital. She has four Emmy nominations for this role and one other previous nomination.
Brandt plays Marie Schrader, a kleptomaniac and wife of a DEA agent. She has no previous Emmy nominations for this role.
Panjabi plays Kalinda Sharma, a law firm's intense private investigator. She has one Emmy win in her two nominations for this role.
Huston plays Eileen Rand, the tenacious producer of a Broadway musical. This is her first time eligible at the Emmys for this role. She has six previous nominations in her career.
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