Only three of her competitors return to possibly contend again in 2013 as Kristen Wiig is no longer on "Saturday Night Live," and Kathryn Joosten ("Desperate Housewives") passed away last year.
Of this trio, Bowen's co-star Sofia Vergara is the strongest threat. She has also contended for all three seasons of the show and is the pick of one editor and 20% of users. That translates into odds of 3 to 1.
While Mayim Bialik ("The Big Bang Theory") is likely to reap her second straight bid for this hit laffer, she has only 2% of users predicting her to prevail. That lack of support gives her odds of only 12 to 1 which puts her in fifth place.
Merritt Wever ("Nurse Jackie") was a surprise nominee in this category last year and with odds of 50 to 1 is unlikely to return this year.
Two women who have contended in this category in the past are poised to make comebacks.
Jessica Walter ("Arrested Development") was a nominee in 2005 for the second season of this laffer and is likely to reap another bid for the return of this cult hit on Netflix. She has the support of 5% of users which is good enough for odds of 8 to 1.
And Jane Krakowski is likely to reap a bid for the final season of "30 Rock." For her fourth nomination (after contending in 2009 - 2011), she is ranked in fourth place with odds of 10 to 1.
Rounding out the race at this point is Allison Williams for the sophomore season of "Girls. While she is not listed first by anyone, her placement on the rankings is good enough to warrant odds of 25 to 1.