Cheadle plays Marty Kaan, a partner on a team of management consultants who travel the world. He has five career Emmy nominations.
C.K. plays Louie, a stand-up comedian and newly divorced father living in New York City. He has one Emmy win in 15 career nominations.
Cryer plays Alan Harper, a chiropractor and free-loader in Malibu. He has one Emmy win in seven career nominations.
David plays a fictional version of himself, the wealthy creator of "Seinfeld" who struggles to conform to society's rules. He has two Emmy wins in 20 career nominations.
Parsons plays Dr. Sheldon Cooper, a former child prodigy and current theoretical physicist who is awkward in social situations. He has two Emmy wins in four career nominations.
Baldwin plays Jack Donaghy, the president of the NBC television network who gets heavily involved in his employees' lives. He has two Emmy wins in 13 career nominations.