[PHOTOS] Oscar Best Actress gallery: Will Natalie Portman (‘Jackie’) be latest to win for real-life role?

If Natalie Portman wins the Best Actress Oscar for “Jackie,” as many experts are predicting, she will join a list of esteemed leading ladies who won for playing real-life roles. The last such winner was Meryl Streep (“The Iron Lady” in 2011), who donned extensive hair and makeup and adapted a British accent in her portrayal of Prime Minister Margaret Thatcher. Who else won for real-life performances? Click through our detailed Best Actress photo gallery above.

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In “Jackie,” Portman takes on the role of First Lady Jackie Kennedy following the 1963 assassination of her husband, President John F. Kennedy. Directed by Pablo Larrain, “Jackie” is expected to be nominated for seven Oscars: Best Actress, Best Original Screenplay, Best Film Editing, Best Cinematography, Best Costume Design, Best Production Design and Best Score. This would be Portman’s second Oscar victory after winning Best Actress for “Black Swan” (2010).

[PHOTOS] Oscar Best Actor gallery:
All 88 winners, from Leonardo DiCaprio to Emil Jannings

Also in the running for this year’s Best Actress prize are several other contenders who portray real-life women: Ruth Negga as interracial marriage plaintiff Mildred Loving in “Loving,” Streep as the titular singer in “Florence Foster Jenkins,” Taraji P. Henson as NASA mathematician Katherine Johnson in “Hidden Figures” and Rachel Weisz as Holocaust professor Deborah Lipstadt in “Denial.” See more Oscar predictions for Best Actress.

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